Current Research Publications

• Ressler KJ, Berretta S, Bolshakov VY, Rosso IM, Meloni E, Rauch SL, and Carlezon WA Jr (2021). Posttraumatic Stress Disorder: Clinical and Translational Neuroscience from Cells to Circuits. Nature Reviews Neurology, in press. DOI: 10.1038/s41582-022-00635-8

• Mahue ME, Sharma S, King G, Maddox SA, Wingo L, Lori A, Michopoulos V, Richardson R, Ressler KJ. (2021) Amygdala DCX and blood Cdk14 are implicated as cross-species indicators of individual differences in fear, extinction, and resilience to trauma exposure. Molecular Psychiatry, Epub ahead of print. PMID: 34728797. DOI: 10.1038/s41380-021-01353-1

• Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, Gassen NC, Schmidt MV, Ressler KJ (2021). (2021) Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5. Cell Reports. 35(9):109185. PMID: 34077736. DOI: 10.1016/j.celrep.2021.109185

• Wuchty S, Myers AJ, Ramirez-Restrepo M, Huentelman M, Richolt R, Gould F, Harvey PD, Michopolous V, Steven JS, Wingo AP, Lori A, Maples-Keller JL, Rothbaum AO, Jovanovic T, Rothbaum BO, Ressler KJ, Nemeroff CB. (2021) Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression. Molecular Psychiatry. 2021 May 7. Epub ahead of print. PMID: 33963278. DOI: 10.1038/s41380-021-01084-3

• Wingo TS, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Lori A, Kim PJ, Ressler KJ, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo AP. (2021) Brain proteome-wide association study implicates novel proteins in depression pathogenesis. Nature Neurosci. 24(6):810-817. PMID: 33846625. DOI: 10.1038/s41593-021-00832-6

• McCullough KM, Missig G, Robble MA, Foilb AR, Wells AM, Hartmann J, Anderson KJ, Neve RL, Nestler EJ, Ressler KJ, Carlezon WA Jr. (2021) Nucleus Accumbens Medium Spiny Neuron Subtypes Differentially Regulate Stress-Associated Alterations in Sleep Architecture. Biological Psychiatry. 2021 Jun 15;89(12):1138-1149. PMID: 33715826. DOI: 10.1016/j.biopsych.2020.12.030

• Lori A, Schultebraucks K, Galatzer-Levy I, Daskalakis NP, Katrinli S, Smith AK, Myers AJ, Richholt R, Huentelman M, Guffanti G, Wuchty S, Gould F, Harvey PD, Nemeroff CB, Jovanovic T, Gerasimov ES, Maples-Keller JL, Stevens JS, Michopoulos V, Rothbaum BO, Wingo AP, Ressler KJ. (2021) Transcriptome wide association study of post-trauma symptom trajectories identified GRIN3B as a potential biomarker for PTSD development. Neuropsychopharmacology. 46(10):1811-1820. PMID: 34188182. DOI: 10.1038/s41386-021-01073-8. Link to view the article for free: https://rdcu.be/cLb7O

• Rosso IM, Silveri MM, Olson EA, Jensen JE, Ren B. (2021) Regional specificity and clinical correlates of cortical GABA alterations in posttraumatic stress disorder. Neuropsychopharmacology, in press. DOI: 10.1038/s41386-021-01197-x. Link to view the article for free: https://rdcu.be/cLb7y